Brimstone is a promotional cosmetic item for all classes.It is based on the horns given by Brimstone in the video game The Binding of Isaac: Rebirth; a pair of curved horns.. It can take you to rooms that require bombs/keys, e.g. Brimstone - Official Binding of Isaac Candle. It also doesn't do poison damage despite having the tagline 'toxic aura tears', * item room, treasure room, item room pool, brown, pink, purple, plant, Upon entering every 4th unexplored room, the Broken Watch will either slow down or speed up all enemies in the room, The slow effect is much more common than the speed up, * shop room pool, shop item pool, blue, grey, gray, smashed, clock, broken stop watch, broken stopwatch, A blue boomerang which can be thrown in a similar fashion to Mom's Knife, to stun any enemies it hits and deal damage, The damage dealt by the Boomerang is equal to double your tear damage, The boomerang can also be used to grab pickups and consumables from a distance, similar to the legend of zelda boomerang, The range of the boomerang is affected by range, with number one the distance is very short and makes the item a lot less effective, The Boomerang can be used to kill shopkeeper corpses, allowing you to farm their drops for coins, items, Steam Sale etc, REPENTANCE - Boomerang is now piercing, and has far less downtime between throwing it and being able to fire tears again, * shop room pool, shop item pool, crescent, moon, blue, grey, gray, * boss room pool, boss room item, grey, gray, punk, Decreases the size of Isaac, and your player hitbox, making you less likely to be hit, * boss room pool, boss room item, pro plus, tablet, medicine, white, * boss room pool, boss room item, grey, orange, family, picture, * boss room pool, boss room item, mushroom, fungi, fungus, Item Pool: Boss Room, Gold/Stone Chest, Key Beggar, * boss room pool, boss room item, brass, bronze, brown, gold, REPENTANCE - Also drops the Match Stick trinket, * boss room pool, boss room item, white, red, * boss room pool, boss room item, syringe, needle, grey, purple, pink, * boss room pool, boss room item, the lost item pool, dog, biscuit, brown, orange, A one-time use item which when used, will duplicate any pedestal items or consumables in the current room, If used in a shop, the duplicated items can be taken for free, If used on a trinket, another random trinket will spawn instead of a duplicate, If used in the Boss Rush, all the duplicates can be taken for free as well as one of the original items, If used in a Devil Room or Black Market, the duplicates can be taken for free, When used, copies the effect of the pill you are currently holding without consuming it, The charge time of this item depends on the quality of the pill you're holding, When used, has a 50% chance to drop one random type of coin (penny, nickel or dime), UNLOCK: Unlock this item by donating 33 coins to the Greed Donation Machine, UNLOCK: Keeper starts with this item after beating Isaac with Keeper, With this item, at the start of every room you will deal double your tear damage to the entire room in a poison effect, Enemies killed now also leave a pool of creep on the ground where they died. Unlocked from Challenge #24 - PAY TO PLAY, Power Pill - Gives you invulnerability and the ability to damage enemies for a short while (similar to The Gamekid effect), Re-Lax - Causes Isaac to spawn poops behind him while he walks for a few seconds. Recharge time: Starts at 1 second, increasing by every time you use it. However after the first damage tick, there is an additional pause for ~0.12 seconds (7 frames). The first piece drops by beating the first floor boss within 1 minute then bombing the shadow in the first room. Curses EDIT: NL now has Dead God, items are no longer bolded. Suicide King or using The Bible on Isaac, ??? Counts as 1 of 3 familiar items needed towards the Conjoined transformation. Enemies include Candler, Lil' Haunt, Polty, Red Ghost, Wizoob and The Forsaken, The Haunt, The Heretic and The Rainmaker bosses. *, brown, red, tup, carton, box, golden chest pool, gold chest pool, Item Pool: Boss Room, Gold/Stone Chest, Mom's Chest, *, white, necklace, grey, gray, moms pearls, mom pearls, The Car Battery causes your spacebar item to activate twice on each use, For example, with Yum Heart you would heal 2 full red hearts instead of 1, Upon use, gives you a duplicate of each familiar you have for the current room, It will not 'double' your familiars as the tagline suggests - if you have 2 of one kind, it will only give you an extra one, If the familiar only appears when taking damage (i.e. Each laser is emitted for about one second and hits twice, so it is possible to destroy some two-stage enemies in one shot (Globins and Hives along with the flies they spawn on death), or to strafe the shot over multiple enemies. Notes: Very fun Isaac seed that leads to some interesting synergies, particularly if playing as Azazel. Curses For everything it increases by 1 coin * the number of purchases, The max price of an item is always 99c with this item, Works with Keeper's Box and the Member Card extra shop, Most spider enemies no longer target or deal contact damage to Isaac, This is very similar to a Skatole for spiders instead of flies, Continuously firing or charging tears for 3 seconds causes Isaac to fart and drop a Butt Bomb, Only 1 Butt Bomb can be dropped per charge, so you'll need to stop firing then start again to drop another one, Butt Bombs explode for 50 damage like normal bombs, but also deal 10 damage to all enemies in the room and daze them for a short period of time, *, yfront, y-front, underpants, underwear, white, grey, gray, no 2, number two, number 2, no two, Transforms Isaac's tears into a wide arc shape which doubles their size and hitbox, *, flat, white, grey, gray, blue, drip, water, eyes, This item turns all doors that require a key into doors which need a coin to enter instead, This affects shops, item rooms, libraries, double locked doors, key blocks, chests and other key doors, Changes the appearance of doors and objects that this item works on to show a coin slot instead of a keyhole, Item Pool: Shop, Greed Mode Item Room, Greed Mode Shop, *, grey, gray, metal, slot, rectangle, silver, Gives you a random item at the start of your next run (You need to start a fresh run to receive the item), Important progression items such as Key Pieces or the Mom's Shovel pieces cannot be given by Eden's Blessing, UNLOCK: Unlock this item by beating Blue Womb (Hush) with Eden, When used, can be thrown at enemies to capture them (similar to a Pok Ball), After capturing an enemy, the next use of the Friendly Ball will re-spawn the same enemy as a friendly companion which will attack other enemies, The companion will persist between rooms and floors until it dies by taking enough damage, Walking over the thrown ball after capturing an enemy will immediately recharge it, *, pokemon, grey, gray, blue, deathstar, circle, When used, will detonate any tears currently on the screen and cause each one to split into 6 more tears which will fire in a circle, similar to Tammy's Head, Luck-based items such as Holy Light are applied to each tear individually, Gives Isaac a familiar Gurdy that will charge around the room dealing contact damage to enemies, The Gurdy is charged by holding down the fire button and letting go. Based on the Steam Workshop mod created by by Scayze and Ashkait, *, bloody, paper, script, white, red, toilet paper, seven seals. If you have 40 bombs it will spawn 4 x Boom! Gives a small chance when entering a room for enemies to be petrified for 4 seconds. Cain - +1 Luck. Also got libra but just a basic all stats up. - Gives the curse of the maze effect for the current floor. The effect triggers again 30 seconds after use and again 60 seconds after use, Something's wrong - Spawns a pool of black creep beneath Isaac, Vurp! Tainted Eve starts with 2 red . red, pink, broken, Better chance to win while gambling at the Shell Game and Fortune Telling Machine, Higher chance to get a random drop after clearing a room, REPENTANCE - Lucky Foot now guarantees positive pill effects, * normal beggar pool, normal judgement pool, coin beggar pool, coin judgement pool, item room, treasure room, item room pool, starting, pink, white, yellow, A target is placed on the floor which can be controlled. : No effect. Both the box and trinket are consumed when this happens, UNLOCK: Unlock this trinket by defeating Isaac, ?? Any subsequent hits give +0.4 Tears Up and will ignore the normal fire rate cap, Greatly decreases damage (x0.33 damage multiplier), Individual tears gain random worm effects (e.g. Further Reading: The Binding of Isaac: Repentance Review; Version 1.78 brings with it a plethora of gameplay changes, which we know you're itching to check out. Blood Clot - Unless playing as Cain, no damage or range bonus will be given from the item, as the blood clot covers the other eye. 111 will tell you what to do. While you have this flame you also have that item's effect, The flame deals double your tear damage to any enemies that touch it, but if it takes too much damage the flame will disappear and you lose the item's effect, Wisps are randomly chosen from Item Room, Boss Room and Shop item pools, with a 25% chance to pick the same pool as the current room. If used in a room with no enemies, Dark Esau will instantly spawn, Will chain up to two targets if you have Car Battery, if only one valid target is present it will be chained for twice the duration, UNLOCK: Unlock this item by defeating Delirium as Tainted Jacob, Rerolls all pedestal items, lowering all their internal item IDs by 1, For example: Brimstone's ID = 118, so it would be rerolled into Dead Bird (ID = 117), Sad Onion (ID = 1) will reroll into nothing, There are some gaps in item IDs which are skipped if no item exists, or will reroll into unexpected items if hidden items are present at that ID. While in a Red room, the chances to spawn a Red Room are: 1 Key = 12.5% chance. Smaller enemies spawn 2-3 tears, and bosses spawn a maximum of 16, Tears from this effect maintain tear modifiers and status effects that Isaac currently has, Isaac doesn't take damage from the tears created by this item, Every time you take damage, a tiny Isaac familiar will spawn, which follows you and shoots tears at nearby enemies that deal 1.3 Damage, The mini-Isaacs stay with you between floors, but can die if they take too much damage, Maximum number of mini-Isaacs is 16 at one time, Mini-Isaac's keep some of the abilities and appearance that Isaac has - e.g. It also leaves a gas cloud at the place where it exploded, The bomb deals 185 damage + your tear damage on hit and leaves a damage over time poison effect that does 3 times your tear damage per tick, Synergizes with tear modifying items such as My Reflection or Tiny Planet, Has a chance to drop from the Sloth miniboss fight, Counts as 1 of 3 poison items needed towards the Bob transformation, REPENTANCE - The damage of this item was significantly boosted to 185 (from 50) in Repentance, and given the poison cloud effect. When the charge bar gets to zero it will grant you a brief period of invincibility, If the spacebar is held for too long (about 1 second) when it has no charge, you will take damage, During the invincibility period, Isaac deals 3.5 contact damage to enemies and beams of light will strike down from the sky, dealing 15 damage, If damage is blocked perfectly at the exact second the charge bar reaches zero, it will release holy beams in four directions and grant a brief shile effect, The invincibility effect is shown via a rapid flashing animation, * angel room pool, god room pool, angel room item, white, blue, ball, circle, After taking damage, if you have half a red heart or less, The Polaroid will give you an invincibility shield for 5 seconds, Allows you to open the door at the beginning of Depths II that leads to the Mausoluem, When unlocked, is guaranteed to drop after the Mom's Foot boss fight, The Polaroid will always spawn on the left pedestal, UNLOCK: Unlock this item by beating Isaac in the Cathedral 5 times, After taking damage, if you have half a red heart or less, The Negative will deal 40 damage to all enemies in the room, The Negative will always spawn on the right pedestal, UNLOCK: Unlock this item by beating Satan in Sheol 5 times, * mom's foot, mom fight, mom boss, dark room, photo, family, kodak, inverted, You no longer shoot tears and instead now control a single large tear with the arrow keys, Items which increase your tears stat will cause the tear to deal damage at a faster rate, Items which increase your shot speed cause the tear to travel faster across the screen, Ludo and Brimstone create a large controllable red ring of death that does massive damage to anything in its path, Taking this with Mom's Knife allows you to remote control the knife around the room, dealing huge damage, * item room, treasure room, item room pool, eye, pink, grey, gray, robot, REPENTANCE - Soy Milk tears now cause drastically less knockback, * item room, treasure room, item room pool, white, glass, square, Isaac's tears become homing and have an aura around them, which will deal a flat 2 damage per tick to anything inside its radius, Multiple GodHeads doesn't stack the aura damage, UNLOCK: Unlock this item by completing all post-it note marks in hard mode with The Lost character, * angel room pool, god room pool, angel room item, yellow, blue, red, triangle, all seeing eye, Gives Isaac an extra life on death, exactly the same as Lazarus' default respawn effect, When you die with this item, you respawn in the same room with 1 heart and the Anemic item, The game considers you to be a different character (Lazarus II) when this effect activates, UNLOCK: Unlock this item by beating the Isaac boss with Lazarus, * angel room pool, god room pool, angel room item, item room, treasure room, item room pool, Will take red hearts first before any other, Eve starts with this item after donating 439 coins to the Greed Donation Machine, UNLOCK: Unlock this item by beating Satan with Eve, Item Pool: Item Room, Curse Room, Demon Beggar, * devil pool, devil room pool, devil deal, the lost item pool, starting, silver, grey, gray, Upon use, this item refreshes the current floor with brand new rooms, monsters and items, as if you had entered a new floor, UNLOCK: Unlock this item by beating Satan with Blue Baby, Item Pool: Item Room, Secret Room, Devil Room, Demon Beggar, * secret room pool, item room, treasure room, item room pool, pill, tablet, drug, white, The chemical signals travel through your blood to the spleen, where many platelets are stored. )[Check ingame], PC B8TK KNEP (Second floor Devil Room.) Items This doesn't convert hearts that dropped before picking up this trinket, and doesn't apply to set heart drops, i.e. This gives you his ability to fly, and the Holy Mantle effect. If you get hit in either of the other 2 states you will not be teleported, The Black Candle item will remove the Cursed Eye's teleportation effect, REPENTANCE - Burst now has 5 shots instead of 4, * secret room pool, item room, treasure room, item room pool, white, circle, pearl, When Isaac's tears hit anything, they leave a green toxic creep on the floor that damages enemies for 1 damage per tick, * item room, treasure room, item room pool, mystery liquid, grey, gray, green, A familar that is attached to Isaac, which will seek out and damage any enemies close by for 3 contact damage, * astrology, astronomy, item room, treasure room, item room pool, blue, glow, A familiar eye that follows Isaac and copies all his tear modifiers/effects, but shoots in random directions, Tears from this familiar deal 75% of Isaac's tear damage, UNLOCK: Unlock this item by beating Boss Rush with Cain, * item room, treasure room, item room pool, eyeball, white, circle, cataract, cains other eye, A familiar fly that can be moved around via use of the arrow keys dealing 2.5 contact damage per tick, similar to the Ludovico Technique's mechanic, UNLOCK: Unlock this item by beating Boss Rush with Blue Baby, * item room, treasure room, item room pool, blue fly, big fly, blue baby's only friend, fat, dead, ?? The laser deals damage equal to Isaac's damage and deals damage each tick. You can force spawn a cracked key by droping any trinket in a Boss Room or Item room, on any floor on your way down to Depths II. (6 full hearts to fully charge), Unless fully charged, hearts picked up are consumed by the Alabaster Box, instead of being added to your life total. 8 coins = Slot Machine, While playing as Tainted Cain you get a visual interface to see what items are in the bag, allowing you to see what item will be created and swap out specific consumables, Has other uses - Will deal 3 damage to enemies it hits, and can be used to quickly push bombs and objects across rooms, Tainted Cain starts with this item, but can be used by any character after unlocking it and finding it in the item room, Cannot be used to craft another Bag of Crafting, UNLOCK: Unlock this item by defeating Delirium as Tainted Cain, While holding flip, a ghost item will appear behind item pedestals upon entering Item Rooms and Shop that cannot be interacted with, When activated, all real items in the room will be swapped with the ghost items behind them, The ghost item stays there even if you take the regular item, allowing you to use Flip to get both of them, Does nothing with item pedestals that don't have a ghost item behind them, When playing as Tainted Lazarus, activating Flip also changes you between Lazarus and Dead Lazarus, Tainted Lazarus starts with this item, but can be used by any character after unlocking it and finding it in the item room, UNLOCK: Unlock this item by defeating Delirium as Tainted Lazarus, When used, gives you an orbital flame which represents another random passive item in the game. The barrage size is 8 without any multi-shot effect. The achievement 'Sumptorium' is unlocked by defeating Delirium as Tainted Eve, When used, this will retreive the Tainted Forgotten's skeleton back to its owner's hands from any distance, Tainted Forgotten's Birthright effect. are now magnetically attracted to Isaac's tears, Can cause some enemies to have unpredictable movement, * item room, treasure room, item room pool, grey, gray, magnet, Tears are now charged up and fired rapidly in a burst of up to 5 shots at once, The amount of tears fired in the charge depends on how long you charge for, The eye has three states, white (not firing), black (first second of charging) and blinking between black and white. It isn't 100% effective but the effect is very strong and will deflect most shots under a bullet hell situation. Doesn't work with Chocolate Milk. This is shown by the Azazel skin spreading on Isaac's face, After 4 rooms, Isaac's face will flash red. Based on the Steam Workshop mod created by Eufuu, UNLOCK: Unlock this trinket by having a lot of blue flies at once, While held this trinket gives your familiars homing shots, Added as part of the Afterbirth+ Booster Pack #5. Increases the maximum heart limit to 18. treasure room, item room pool, yellow, golden, ring, circle, Item Pool: Item Room, Shop, Challenge Room, Beggar, Demon Beggar, Mom's Chest, * dungeon room, blood challenge room, arena pool, demon beggar pool, demon judgement pool, devil beggar pool, normal beggar pool, normal judgement pool, coin beggar pool, coin judgement pool, shop room pool, shop item pool, item room, treasure room, item room pool, yellow, red, blue, medicine, jar, drug, moms bottle of pills, Tears now have a random chance to apply a poison effect, causing double your tear damage per tick to enemies over time, The chance to fire poison shots is affected by your luck stat and at +12 Luck it will activate every time, * item room, treasure room, item room pool, green, snot, booger, ball, slime, Isaac's tears now split into two upon contact with enemies or the environment, Tears that split off from the main tear do less damage (tear damage * 0.5), Tears can keep splitting if they still have range and damage above 1, UNLOCK: Unlock this item by collecting two of the following items: Bob's Rotten Head, Dead Cat, Cricket's Head, Tammy's Head, * item room, treasure room, item room pool, pink, slug, bug, face, When used, replaces all pedestal items in the current room with another random item. (page 3, column 6, row 3)(page 2, column 6, row 6). The spear occasionally inflicts fear on enemies it damages. effect for the floor, UNLOCK: Unlock this item by beating Satan with Eden, Item Pool: Item Room, Library, Secret Room, * library pool, library room, book room pool, secret room pool, item room, treasure room, or the path they take (My Reflection, Tiny Planet etc. Rooms While held there is a small chance when using a tarot card or pill that a copy of it will be dropped on the floor next to you, +0.2 Damage Up for each 'evil' item you have, Items classed as evil in this case are Black Candle, Ceremonial Robes, Abaddon, Goat Head, Match Book, Missing Page 2, Safety Pin, UNLOCK: Unlock this item by beating Greed Mode with Eve, Invincibility lasts longer after getting hit (Increased i-frames), This makes it possible to use the Blood Donation machine twice from one hit of damage, UNLOCK: Unlock this item by beating Blue Womb (Hush) with Samson, *, bandana, sling, white, knot, blindfold, +15% chance to get a double item room to spawn on the next floor, If the effect activates, two items spawn in your item room, however only one can be taken (Same effect as the More Options item), The chance doubles to +30% with the effect from Mom's Box, Automatically opens all shop room doors for free, UNLOCK: Unlock this trinket by donating 666 coins to the Greed Donation Machine, UNLOCK: Keeper starts with this trinket after beating Satan with Keeper, Forces the Greed and Super Greed mini bosses to no longer appear in shops or secret rooms, Holding Rib of Greed increase your chance to receive coin drops, UNLOCK: Unlock this trinket by beating Ultra Greed with Keeper, Donating to a Donation Machine has a chance to heal Isaac for a full red heart or spawn a Beggar, UNLOCK: Unlock this item by beating The Lamb boss with Keeper, Destroying poops now gives you a blue fly, While held, you heal for half a red heart every time you use a key to open a door or golden chest, Changes all half red hearts into full hearts, Hearts dropped from Tainted Magdalene's mechanic will be always full red hearts, *, red, brown, grey, gray, necklace, moms locket, mom locket, While this trinket is held you have a significantly lower chance to find spacebar/active items, It will cause passive items to spawn except when the game cannot generate any more passive items and will then instead choose spacebar/active items, Some hard coded spacebar items from bosses and mini-bosses (i.e. REPENTANCE - This item was completely reworked for Repentance and no longer forces a random dice use each time. grey, gray, feet bobby bomb, When used, deals damage to Isaac in exchange for +1.2 damage up which lasts for the current room, The first use per room takes 1 full heart, then 0.5 hearts per use after that. The special shop contains various consumables and items at a higher price from the Devil/Angel room, Boss room and Secret room pools. Yeah I saw one of those rooms on the map too. white, grey, gray, A familiar that follows isaac around dropping white creep which slows down enemies that walk over it, Spawns 1-2 familiar blue spiders after every room, * item room, treasure room, item room pool, white, ball, dripping, A familiar that is controlled via the arrow keys and will automatically fire a laser if anything is in its line of sight, Robo-Baby 2.0's lasers deal 3.5 damage per hit, UNLOCK: Unlock this item by beating Challenge #16 (Computer Savvy), * robo baby 2.0, item room, treasure room, item room pool, red, eyes, grey, gray, robot, A familiar which follows Isaac and spawns a blue flies as you're firing tears, Rotten Baby can only create one fly at a time, meaning if he has created a fly he cannot make another until it is used, * devil pool, devil room pool, devil deal, item room, treasure room, item room pool, dead, baby, Flash Red small chance when entering a room for enemies to be petrified for 4.. 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