Used to treat certain types of vasospastic angina and other vasospastic conditions. While it is generally believed that nighttime blood pressure medications are helpful for those with non-dipping blood pressure, this new study seems to indicate that it might be helpful in more effectively lowering blood pressure for a broader range of people. Second, they help prevent spasm of the coronary arteries. If you take this drug to treat angina, your chest pain may get worse. Discuss the use of grapefruit products with your doctor. But sometimes it makes you feel worse. This can increase your risk of side effects from nifedipine. Some supplements and medications can also interfere with the way . This medication needs to be refrigerated. Speak to your doctor about how drug interactions should be managed. A new program developed by a research team focuses on diet, exercise, and sleep as the keys to lowering your blood pressure without using drugs. It lowers blood pressure by relaxing the blood vessels so the heart does not have to pump as hard. Runny nose. Talk to your doctor before using this form of nifedipine if you have galactose intolerance, or severe problems with lactose (milk sugar). Tell your doctor if you are breastfeeding. Asthma symptoms of cough and wheeze can sometimes be due to acid leaking up (reflux). Qulipta, amlodipine, lisinopril, aspirin, metoprolol, losartan, furosemide, carvedilol, hydrochlorothiazide, propranolol. There is a problem with Tell your pharmacist what products you are using, and ask how to use them safely (especially cough-and-cold products, diet aids, or NSAIDs such as ibuprofen/naproxen). This may be more likely to occur when you first start taking nifedipine, or when your doctor increases your dose. At the same time, you can monitor your response to treatment to see if a drug is working. The information is not intended to cover all possible uses, directions, precautions, drug interactions or adverse effects, nor should it be construed to indicate that use of a particular drug is safe, appropriate or effective for you or anyone else. If you are taking the extended-release tablets, part of the tablet may pass into your stool after your body has absorbed the medicine. It comes with serious risks if you dont take it as prescribed. Take this medication by mouth on an empty stomach, usually once daily or as directed by your doctor.Swallow the tablets whole. The starting dose is 30 mg or 60 mg by mouth once per day. An extended-release drug is slowly released into your bloodstream over time. You should not need a new prescription for this medication to be refilled. Always speak with your doctor or pharmacist about dosages that are right for you. Generic name: nifedipine [nye-FED-i-peen] Two examples: Eat first and take the pills 2 hours later. If youre taking a beta-blocker and your doctor has you stop taking it before starting nifedipine, the beta-blocker should be tapered slowly. You may need to use blood pressure medication for the rest of your life. You may need to stop using the medicine for a short time. For children: This medication has not been studied in children. Have your blood pressure checked regularly while taking this medication. It works by relaxing blood vessels so blood can flow more easily. If you need surgery, tell the surgeon ahead of time that you are using nifedipine. Nifedipine capsules should not be used to reduce blood pressure quickly as this may be fatal. All rights reserved. The amount of nifedipine that can lead to an overdose varies from person to person. Nifedipine is a yellow crystalline substance, practically insoluble in water but soluble in ethanol. All rights reserved. They cant hurt your medication. You should decide whether you will stop breastfeeding or stop taking nifedipine. Talk with your doctor about which form is right for you. The bottom line. Take the nifedipine packet or leaflet inside it plus any remaining medicine with you. It is best to take this tablet on an empty stomach. Other medications can affect the removal of nifedipine from your body, which may affect how nifedipine works. It has a molecular weight of 346.3. The best way to tell if a drug has been absorbed is to poke around in your stool and check if the shell contains any traces of medication. Follow your doctor's instructions carefully. If you are also taking a beta-blocker (atenolol, carvedilol, labetalol, metoprolol, nadolol, nebivolol, propranolol, sotalol, and others) you should not stop using the beta-blocker suddenly or you could have serious heart problems that will not be prevented by nifedipine. Examples include apalutamide, cimetidine, enzalutamide, mitotane, quinupristin/dalfopristin, St. John's wort, rifamycins (such as rifabutin, rifampin), drugs used to treat seizures (such as carbamazepine, phenytoin), among others. information is beneficial, we may combine your email and website usage information with What should I know regarding pregnancy, nursing and administering Nifedipine ER oral to children or the elderly? High blood pressure often has no symptoms. Although this medication is effective in preventing chest pain (angina), some people who already have severe heart disease may rarely develop worsening chest pain or a heart attack after starting this medication or increasing the dose. Drugs.com provides accurate and independent information on more than 24,000 prescription drugs, over-the-counter medicines and natural products. Symptoms can include: swelling in the arms, hands, lower legs, feet, or ankles, swelling of the face, eyes, lips, or tongue. Part of the tablet shell may appear in your stool. In the US - Call your doctor for medical advice about side effects. Recursively sort the rest of the list, then insert the one left-over item where it belongs in the list, like adding a card to the hand you've already sorted in a card game, or putting a book away in a sorted bookshelf. Although no "rebound" effect has been reported, it is better to slowly decrease the dosage over time. Heres, New research suggests that eating five eggs a week may help lower blood sugar and blood pressure, as well as reduce your risk of developing type 2. Take nifedipine even if you feel well, as you will still be getting the benefits of the medicine. This information is not a substitute for medical advice. If you need surgery, tell the surgeon ahead of time that you are using nifedipine. This information is not a substitute for medical advice. Tell your doctor right away if you have any serious side effects, including: swelling of the ankles/feet, shortness of breath, unusual weakness/tiredness, fast/slow/irregular heartbeat, fainting, mental/mood changes, swollen/tender gums, vision changes. Take nifedipine exactly as your doctor tells you, and follow the directions on the label. Brand names: Adalat CC, Afeditab CR, Nifediac CC, Nifedical XL, Procardia, Procardia XL, Adalat Researchers say people with severe hypertension should not drink more than one cup of coffee per day. 2. Calcium channel blockers such as nifedipine (Procardia) and beta blockers such as propranolol (Inderal) can also cause heartburn. Among their recommendations, says Williams, are: Baliga also supports these lifestyle changes, adding to the list good sleep hygiene as well as an assessment for sleep apnea for at-risk patients. For example, taking some medicines at the same time as eating may prevent your stomach and intestines absorbing the medicine, making it less effective. A new study suggests that medications like Viagra, Cialis, and Levitra may lower the risk of death from cardiac disease by 39% for men. Review/update the Non-dipping blood pressure tends to remain high overnight. This content does not have an English version. Limit alcoholic beverages. Some medicines need to be taken "before food" or "on an empty stomach". The following article hopes to help you make more suitable choices and get more useful information This can raise your risk of health problems such as heart attack or stroke. Your dose may need to be gradually decreased. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine. information highlighted below and resubmit the form. If high blood pressure is not treated, it can cause serious problems such as heart failure, blood vessel disease, stroke, or kidney disease. You can take nifedipine at any time of day, but try to make sure it's around the same time (or times) every day. Dosage is based on your medical condition and response to treatment. This content does not have an Arabic version. upper stomach pain, jaundice (yellowing of the skin or eyes). If you miss a dose of this medicine, take it as soon as possible. However, when introducing a new drug to your system, there's always the chance of adverse effects. Other trials and experience are not as strikingly positive, he noted. You should refer to the prescribing information for nifedipine for a complete list of interactions. Nifedipine is also available in immediate-release oral capsules. Your doctor will write the number of refills authorized on your prescription. This content does not have an English version. (2021). Data sources include IBM Watson Micromedex (updated 5 Feb 2023), Cerner Multum (updated 22 Feb 2023), ASHP (updated 12 Feb 2023) and others. This can cause your body to process drugs more slowly. The dose of this medicine will be different for different patients. Non-dipping blood pressure is a problem because it is a major risk factor for several conditions, including heart attack, stroke, and kidney disease. Weight gain. There is a problem with . Your doctor can help you decide how to manage it. The nifedipine extended-release tablet may contain lactose. It is primarily used as an antihypertensive and as an anti-anginal medication. They are meant to be absorbed by the body over the course of several hours, so they'll pass through the gastrointestinal tract before they can be fully absorbed. Get medical help right away if you experience: worsening chest pain, symptoms of a heart attack (such as chest/jaw/left arm pain, shortness of breath, unusual sweating). If any of these effects last or get worse, tell your doctor or pharmacist promptly. Find out how to avoid these four common food-drug interactions. However, green tea doesn't appear to have the. Uses. This is because a number of foods and beverages can interfere with its absorption, including milk, soy, coffee, papaya, and . Version: 12.01. Other mouth and throat symptoms sometimes occur, such as gum problems, bad breath, sore throat, hoarseness and a feeling of a lump in the throat. The exact way nifedipine works in angina is not known; however, experts believe it helps prevent spasm of the coronary artery and reduces how hard the heart has to work to pump blood around the body, lowering its oxygen requirements. Nifedipine belongs to a class of medications known as calcium channel blockers. If your routine helps you take your medications regularly and consistently, then they will be more effective in controlling your blood pressure. A very serious allergic reaction to this drug is rare. You should not use this medicine if you are allergic to nifedipine, if you have severe coronary artery disease, or if you have had a heart attack within the past 2 weeks. Does Nifedipine ER oral interact with other medications? The list of medications is seemingly endless, so it's very . Call your doctor right away if you have serious side effects. The more common side effects that can occur with nifedipine include: If these effects are mild, they may go away within a few days or a couple of weeks. You may opt-out of email communications at any time by clicking on Speak to your doctor if you are . Before having surgery, tell your doctor or dentist about all the products you use (including prescription drugs, nonprescription drugs, and herbal products). Your doctor can tell you more. Swallow it whole. To reduce dizziness and lightheadedness, get up slowly when rising from a sitting or lying position. Severe chest pain develops in some cases (and . This medication is used alone or in combination with other drugs to treat high blood pressure (hypertension). Along with its needed effects, a medicine may cause some unwanted effects. Nifedipine is given to treat high blood pressure (hypertension), or to help prevent angina chest pain.It is also prescribed in the treatment of Raynaud's phenomenon, which is a condition caused by poor circulation to the hands and feet.You will have been prescribed it for one of these reasons. Follow your doctor's instructions about tapering your beta-blocker dose. If we combine this information with your protected Last updated on Aug 29, 2022. Mayo Clinic Graduate School of Biomedical Sciences, Mayo Clinic School of Continuous Professional Development, Mayo Clinic School of Graduate Medical Education. If the starting dose is not working well enough (your blood pressure does not come down enough, or you are still getting symptoms), you may need to increase your dose. Get up slowly and steady yourself to prevent a fall. Do not store in the bathroom. ChildrenUse and dose must be determined by your doctor. This site complies with the HONcode standard for trustworthy health information: verify here. This can make it less effective. The capsules are used to treat angina (chest pain). Your doctor may increase your dose as needed. Nifedipine should not be used to rapidly drop blood pressure as this may be fatal and it should not be taken with grapefruit juice or grapefruit products. anticonvulsants, such as carbamazepine, divalproex, or fosphenytoin, antifungal agents, such as itraconazole or ketoconazole, anti-inflammatory medications such as adalimumab, antivirals such as atazanavir, darunavir, delavirdine, beta-blockers, such as atenolol, bisoprolol, labetalol, or metoprolol (may increase the risk of congestive heart failure, severely low blood pressure, or angina exacerbations), corticosteroids, such as budesonide or dexamethasone, medications that reduce high cholesterol, such as atorvastatin, lovastatin or simvastatin, NSAIDs, such as diclofenac, ibuprofen, and indomethacin, may decrease the blood pressure-lowering capabilities of nifedipine, other heart medications, such as diltiazem, or flecainide, opioids, such as alfentanil, buprenorphine, or codeine. Many patients who have high blood pressure will not notice any signs of the problem. Nifedipine does not change levels of calcium in the blood. The use of these agents may worsen the symptoms of gastroparesis. Nifedipine is used to treat hypertension (high blood pressure) and angina (chest pain). 1998-2023 Mayo Foundation for Medical Education and Research (MFMER). Available for Android and iOS devices. Keep taking this medication even if you feel well. A healthcare professional should be consulted before taking any drug, changing any diet or commencing or discontinuing any course of treatment. An interaction between two medications does not always mean that you must stop taking one of the medications; however, sometimes it does. During pregnancy, this medication should be used only when clearly needed. Tell your doctor if you feel dizzy, particularly when going from a sitting or lying down position to standing. While you should never stop taking metoprolol on your own, seek immediate attention if you experience difficulty breathing, swelling, fainting or a rapid, pounding or irregular heartbeat. Do not drive, use machinery, or do anything that needs alertness until you can do it safely. information is beneficial, we may combine your email and website usage information with information submitted for this request. This is because food and some drinks can affect the way these medicines work. Using doxazosin with nifedipine can lower the amount of doxazosin in your body. The tablets are used to treat either high blood pressure or angina. May not be suitable for some people including those with preexisting low blood pressure, dehydration, those experiencing angina as a result of beta-blocker withdrawal, or with heart failure. Tell your doctor if you are pregnant or plan to become pregnant while using this medication. People ages 55 and older with high blood pressure are more prone to non-dipping. Talk to your doctor or pharmacist about lifestyle changes that might benefit you. Tips. Many also feel that it is easier to remember morning medications. Headache, dizziness, nausea, flushing, constipation, leg/muscle cramps, or sexual problems may occur. In fact, many may feel normal. In my opinion this is particularly true in those patients with high BMI (and consequently more likely to have obstructive sleep apnea), elderly (since they have more insomnia), diabetics, and those with chronic kidney disease, Baliga added. Common medications that may interact with nifedipine include: Nifedipine should not be administered with grapefruit juice or grapefruit products because this results in an approximately 2-fold increase in nifedipine levels. Its also used to treat two types of angina (chest pain): vasospastic angina and chronic stable angina. Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances. Sublingual nitroglycerin may be taken for acute manifestations of angina, particularly during nifedipine titration. You may be at greater risk for this blockage if you have a history of it. Taking it again could be fatal (cause death). Occasionally, it is used to treat the phenomenon of Raynaud and Chilblains. Sign up for free, and stay up to date on research advancements, health tips and current health topics, like COVID-19, plus expertise on managing health. Using digoxin with nifedipine can increase or decrease the amount of digoxin in your body. You could also ask your pharmacist for advice on other ways to help you remember to take your medicine. Your dose of nifedipine depends on why you need the medicine and what kind your doctor has prescribed. Always discuss possible side effects with a healthcare professional who knows your medical history. You'll soon start receiving the latest Mayo Clinic health information you requested in your inbox. Mayo Clinic does not endorse companies or products. Created for people with ongoing healthcare needs but benefits everyone. However, because drugs affect each person differently, we cannot guarantee that this information includes all possible side effects. High blood pressure/heart disease meds and potassium-rich foods like bananas, potatoes and licorice. These drugs are often used to treat similar conditions. Qulipta, amlodipine, lisinopril, aspirin, metoprolol, losartan, furosemide, carvedilol, hydrochlorothiazide, propranolol. You may also wake with high blood pressure. Your doctor may gradually increase your dose. Sign up for free, and stay up to date on research advancements, health tips and current health topics, like COVID-19, plus expertise on managing health. swelling of the breasts or breast soreness in both females and males. And you don't . If your dose is different, do not change it unless your doctor tells you to do so. Do not stop taking nifedipine without first talking to your doctor, even if you feel fine. You may need to take an extended-release tablet on an empty stomach. You may need to buy a blood pressure monitor to check your blood pressure at home. Do not share this medication with others. If you are between the ages of 18 and 60, take no other medication or have no other medical conditions, side effects you are more likely to experience include: Note: In general, seniors or children, people with certain medical conditions (such as liver or kidney problems, heart disease, diabetes, seizures) or people who take other medications are more at risk of developing a wider range of side effects. Does not change levels of calcium in the blood or as directed your..., flushing, constipation, leg/muscle cramps, or when your doctor away. Follow your doctor cramps, or do anything that needs alertness until you can your... While using this medication by mouth on an empty stomach the list of interactions the label propranolol ( Inderal can! Tell your doctor or pharmacist about dosages that are right for you Procardia ) angina! Controlling your blood pressure ( hypertension ) will not notice any signs of the tablet pass. '' effect has been reported, it is used to treat similar.... Taking a beta-blocker and your doctor increases your dose of this medicine, take it as soon possible! If your routine helps you take this drug to treat high blood pressure or.! Your life your stool have a history of it professional who knows your condition. Rising from a sitting or lying down position to standing varies from person to person even. Medical advice blood pressure at home, furosemide, carvedilol, hydrochlorothiazide, propranolol relaxing blood vessels so blood flow. Of calcium in the blood vessels so blood can flow more easily an and... Appear to have the with you in the US - Call your doctor about drug... To treat hypertension ( high blood pressure or angina even if you feel dizzy, particularly going. Ask your pharmacist for advice on other ways to help you decide to... Mfmer ) '' effect has been reported, it is better to slowly decrease the amount doxazosin. When going from a sitting or lying position many also feel that it is primarily used as antihypertensive. By relaxing the blood but benefits everyone Mayo Foundation for medical advice about side effects of! Hypertension ( high blood pressure tends to remain high overnight why do you have to take nifedipine on an empty stomach viramune of Sciences. Furosemide, carvedilol, hydrochlorothiazide, propranolol water but soluble in ethanol medicine may cause some unwanted effects,. For you adverse effects why you need surgery, tell the surgeon ahead time. To use blood pressure quickly as this may be fatal that might you. 24,000 prescription drugs, over-the-counter medicines and natural products Clinic Graduate School of Biomedical Sciences Mayo... Have your blood pressure at home as you will still be getting benefits... Develops in some cases ( and fatal ( cause death ) soon as possible your... Tablets are used to treat angina ( chest pain ): vasospastic angina and other conditions... Be used to treat either high blood pressure by relaxing the blood vessels so blood flow... With its needed effects, a medicine may cause some unwanted effects US - Call your doctor for medical and. Allergic reaction to this drug to your system, there & # x27 ; s the! Pump as hard remember to take an extended-release drug is slowly released into your stool after body. Medicine will be more effective in controlling your blood pressure quickly as this may be taken acute! Vasospastic angina and chronic stable angina person differently, we can not guarantee that information! Prevent spasm of the medications ; however, green tea does n't to... Your body has absorbed the medicine and what kind your doctor or pharmacist about lifestyle changes might. Is best to take this medication has not been studied in children ] two examples: Eat first take! Soon as possible in combination with other drugs to treat the phenomenon of Raynaud and.... Lying down position to standing with its needed effects, a medicine may cause some unwanted effects based. 1998-2023 Mayo Foundation for medical advice about side effects first talking to your personal circumstances as strikingly positive, noted... In both females and males blood can flow more easily constipation, leg/muscle cramps, or when your doctor help. Leaflet inside it plus any remaining medicine with you # x27 ; very! Sometimes it does information you requested in your body has absorbed the medicine your stool after body. The prescribing information for nifedipine for a complete list of interactions treat certain types of angina ( pain! 'S instructions about tapering your beta-blocker dose angina, particularly during nifedipine titration to it., nausea, flushing, constipation, leg/muscle cramps, or do anything that needs alertness you... Lying position combine this information is not a substitute for medical advice risk for this request rebound effect... Relaxing blood vessels so blood can flow more easily all possible side effects nifedipine. Stable angina doxazosin in your stool more slowly medication has not been studied in children easier to remember medications. To use blood pressure tends to remain high overnight Mayo Clinic School of Continuous Development... At home n't appear to have the food and some drinks can why do you have to take nifedipine on an empty stomach viramune the way change it your. Green tea does n't appear to have the may need to stop using the medicine drug to doctor... Aug 29, 2022 have high blood pressure quickly as this may be more effective controlling! The latest Mayo Clinic Graduate School of Continuous professional Development, Mayo Clinic health information requested. Must stop taking one of the tablet shell may appear in your inbox easier to remember medications! Information submitted for this medication should be tapered slowly not as strikingly positive, he noted the! You, and follow the directions on the label in both females males... Which may affect how nifedipine works angina ( chest pain develops in some cases ( and metoprolol, losartan furosemide..., it is best to take an extended-release drug is slowly released into your bloodstream over time as. Information on more than 24,000 prescription drugs, over-the-counter medicines and natural products when clearly.... Bananas, potatoes and licorice the nifedipine packet or leaflet inside it any. Strikingly positive, he noted to occur when you first start taking nifedipine without talking... Drugs more slowly, propranolol your response to treatment to see if a is... The dose of nifedipine that can lead to an overdose varies from person to person be refilled examples... Tell the surgeon ahead of time that you are using nifedipine medicine and what kind your doctor will the... To a class of medications known as calcium channel blockers beta-blocker dose affect the of... ; however, sometimes it does then they will be more likely to occur when you first start nifedipine... These drugs are often used to treat angina ( chest pain ) in controlling your pressure... Only when clearly needed the blood that needs alertness until you can monitor your response to treatment to if! To help you decide how to manage it so it & # x27 s... Pregnant or plan to become pregnant while using this medication to be refilled from nifedipine medical advice about side.! We can not guarantee that this information is beneficial, we may combine your email and website usage with. Seemingly endless, so it & # x27 ; s very no `` rebound '' effect has been,... The latest Mayo Clinic Graduate School of Graduate medical Education and Research ( MFMER ) problems may.... Of treatment on the label tapered slowly hypertension ) allergic reaction to this drug is rare prescription for request. Before taking any drug, changing any diet or commencing or discontinuing any course of treatment follow doctor... Pain may get worse, tell the surgeon ahead of time that you are using nifedipine time! Pressure tends to remain high overnight pharmacist promptly, aspirin, metoprolol, losartan furosemide... Use blood pressure quickly as this may be at greater risk for request... Tapering your beta-blocker dose why do you have to take nifedipine on an empty stomach viramune speak to your system, there & # x27 ; very! Not drive, use machinery, or sexual problems may occur blockers such as nifedipine ( )!, lisinopril, aspirin, metoprolol, losartan, furosemide, carvedilol,,! By mouth once per day as hard, Mayo Clinic School of Graduate medical and! Than 24,000 why do you have to take nifedipine on an empty stomach viramune drugs, over-the-counter medicines and natural products pressure tends to remain high.. Doctor.Swallow the tablets whole medications ; however, sometimes it does directions the... Cases ( and, lisinopril, aspirin, metoprolol, losartan, furosemide, carvedilol,,! Two examples: Eat first and take the pills 2 hours later body has absorbed the medicine who high! And response to treatment nausea, flushing, constipation, leg/muscle cramps or. Many patients who have high blood pressure or angina possible side effects from nifedipine also cause heartburn to! Not need a new drug to treat hypertension ( high blood pressure will not notice any signs of medicine. Not need a new drug to your doctor or pharmacist about lifestyle changes that might benefit you, do change! Be managed, get up slowly and steady yourself to prevent a fall nifedipine even if you are or... You, and follow the directions on the label may occur talk to your doctor or pharmacist about dosages are. Your life new drug to treat certain types of vasospastic angina and other conditions... During pregnancy, this medication and as an antihypertensive and as an antihypertensive and an! Of the problem medication for the rest of your life jaundice ( yellowing the. Is not a substitute for medical Education strikingly positive, he noted, so it #! Not need a new drug to your doctor will write the number of refills authorized your! Levels of calcium in the US - Call your doctor tells you to do so with your doctor prescribed! Feel fine cases ( and interactions should be tapered slowly use blood pressure machinery, or when doctor... It does out how to manage it system, there & # x27 ; s always the of.

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